検索結果

Search Results for " anticancer activity "

ターゲット

Apoptosis GSK-3 Autophagy

606

阻害剤

121

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T14066	9-ING-41		Apoptosis , GSK-3 , Autophagy
	9-ING-41 is a glycogen synthase kinase-3 inhibitor.		Apoptosis , GSK-3 , Autophagy
T6357	(S)-crizotinib	ent-crizotinib	Apoptosis , DNA/RNA Synthesis , MTH1
	(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.		Apoptosis , DNA/RNA Synthesis , MTH1
T1488	Procarbazine hydrochloride	NSC-77213 HCl,Procarbazine HCl	DNA Alkylator/Crosslinker , DNA/RNA Synthesis
	Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated, procarba...		DNA Alkylator/Crosslinker , DNA/RNA Synthesis
T28503	Ralitoline	GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum
	Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.
T10721	CD73-IN-1		CD73
	CD73-IN-1 is a CD73 inhibitor with anticancer activity.		CD73
T68159	Tetrazolast		Antifungal
	Tetrazolast has anticancer activity and may have antifungal activity.		Antifungal
T70086	EPZ033294		Others
	EPZ033294 has potential anticancer and antiproliferative activity.		Others
T60002	DC-S239		Histone Methyltransferase
	DC-S239 (DC-S239) is a selective inhibitor of histone methyltransferase SETD7 (IC50 = 4.59 μM) with anticancer activity.		Histone Methyltransferase
T12682	Emzadirib	CYT-0851,RAD51-IN-2	DNA/RNA Synthesis
	Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.		DNA/RNA Synthesis
T13905	Stilbamidine	Ba 2652,Stilbamidin	Antifungal
	Stilbamidine (Ba 2652) has antifungal and anticancer activity and can be used to study multiple myeloma and bladder migratory cell carcinoma.		Antifungal
T60967	Atg4B-IN-2		Phospholipase , Autophagy
	Atg4B-IN-2 is a potent and selective Atg4B inhibitor with anticancer activity that inhibits the activity of Atg4B and PLA2.Atg4B-IN-2 resists the anticancer activity of anti-desiccation-resistant prostate cancer drugs th...		Phospholipase , Autophagy
T8668	HM03		HSP
	HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.		HSP
T20890	Alvespimycin	17-DMAG,KOS1022,KOS 1022,KOS-1022	HSP
	Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.		HSP
T35300	Zeniplatin	Zeniplatinum	Others
	Zeniplatin (Zeniplatinum) is a new cisplatin complex with anticancer activity for the treatment of metastatic melanoma and kidney cancer.		Others
T15390	Glufosfamide	D 19575,Glucosylifosfamide mustard	Others
	Glufosfamide is a novel oxazolophosphamide compound with anticancer activity for the study of advanced non-small cell lung cancer.		Others
T78210	STC-15	STC15	Others
	STC-15 is an orally active and potent METTL3 inhibitor with anticancer activity that inhibits cancer growth and induces anticancer immunity.		Others
T14974	Citenamide	Cytenamide,AY-15613	Others
	Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties.		Others
T13045	Syk-IN-3		Syk
	Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.		Syk
T15205	EL-102	EL102	Microtubule Associated , HIF
	EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.		Microtubule Associated , HIF
T10395L	ATM-3507		Myosin
	ATM-3507 is a protomyosin inhibitor with anticancer activity that inhibits human melanoma and can be used to study ovarian cancer.		Myosin
T4228	Nolatrexed		DNA/RNA Synthesis
	Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.		DNA/RNA Synthesis
T70388L	(R)-Enitociclib		CDK
	(R)-Enitociclib, an enantiomer of BAY-1251152, is a CDK9 inhibitor with anticancer activity.		CDK
T36491	POMHEX		Glucokinase
	Pomhex, a cell-permeable potent enolase inhibitor with anticancer activity, is used in the study of cancer lethality.Pomhex, a racemic mixture, is a potent and selective ENO2 inhibitor.Pomhex is inhibitory to the glycoly...		Glucokinase
T13639	Deferasirox (Fe3+ chelate)		Apoptosis
	Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be used to study iron overload.		Apoptosis
T23115	OXF BD 02	OXFBD02	Epigenetic Reader Domain
	OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.		Epigenetic Reader Domain
T77558	5,7-Dimethoxy-4-methylcoumarin		Antioxidant
	5,7-Dimethoxy-4-methylcoumarin has potential antioxidant antiproliferative and anticancer or activity.		Antioxidant
T25212	CCCI-01	CCCI 01,CCCI01,Centrosome Clustering Chemical Inhibitor-01	Apoptosis
	CCCI-01（Centrosome Clustering Chemical Inhibitor-01） is a centrosome cluster inhibitor. CCCI-01 has anticancer activity, induces apoptosis, and can be used in the study of non-cross-resistant anticancer compounds that bl...		Apoptosis
T60012	HS-243		IRAK , MAPK , CDK
	HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.		IRAK , MAPK , CDK
T25829	Mopidamol	RA233,RA 233,RA-233,Rapenton,OLX 102	PDE
	Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental diabetes.		PDE
T8529	WYC-210		Others
	WYC-210 is a retinoid compound,and with lower anticancer activity		Others
T21773	SP-141	SP 141	Mdm2
	SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.		Mdm2
T15236	Entasobulin		Microtubule Associated
	Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.		Microtubule Associated
T27454	GSK2008607		Raf
	GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers.		Raf
T23512	VU 0364739 hydrochloride	VU 0364739 HCl	Apoptosis , Phospholipase
	VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer...		Apoptosis , Phospholipase
T27257	EMD-503982	EMD503982,EMD 503982	Factor Xa
	EMD-503982 is a potential Factor Xa and Factor VIIa inhibitor with potential anticancer and antitumor activity for the study of thromboembolic and neurological disorders.		Factor Xa
T12577	PTP1B-IN-3		Phosphatase
	PTP1B-IN-3 is a selective and potent PTP1B inhibitor with anticancer activity that inhibits PTP1B and TCPTP.PTP1B-IN-3 is used in the study of diabetes.		Phosphatase
T34602	Selatinib		EGFR
	Selatinib is an orally active and potent dual inhibitor of EGFR and ErbB2 with anticancer activity that inhibits the growth of NCI-N87 tumor cells.		EGFR
T15055	DB04760	MMP-13 Inhibitor	MMP
	DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activity.		MMP
T20158	Phenformin	Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps	Apoptosis
	Phenformin (BRN 1977317) is a biguanide compound with anticancer and anti-glycemic activity, inhibits skin tumor growth and promotes keratinocyte differentiation and apoptosis.		Apoptosis
T16777	ROC-325		Apoptosis , Autophagy
	ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.		Apoptosis , Autophagy
T69742	SRX3177		Epigenetic Reader Domain , PI3K , CDK
	SRX3177 is a novel and potent inhibitor of BRD4, PI3K and CDK.SRX3177 has potential anticancer activity.		Epigenetic Reader Domain , PI3K , CDK
T60852	Anticancer agent 46
	Anticancer agent 46 is a potent anti-cancer agent, showing anti-proliferative activity in cellular assays, with an IC50 of 0.986 μM against MGC803 cells.
T60564	PI3K/Akt/mTOR-IN-2		Apoptosis , Akt , PI3K , mTOR
	PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor.PI3K/Akt/mTOR-IN-2 has anticancer effects and is selective for MDA-MB-231 cells with an IC50 of 2.29 μM.PI3K/Akt/mTOR-IN-2 exhibits anticancer activity and induces c...		Apoptosis , Akt , PI3K , mTOR
T7208	AMD 3465 hexahydrobromide	GENZ-644494 (hexahydrobromide)	HIV Protease , CXCR
	AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.		HIV Protease , CXCR
T62620	ZY-444
	ZY-444 has potential anticancer activity, inhibits PCa cell proliferation and metastasis, and inhibits the growth of subcutaneous tumors.
T77734	ERK5-IN-5		ERK
	ERK5-IN-5 is a potent extracellular signal-regulated kinase 5 (ERK5) inhibitor with anticancer activity and potential anticonvulsant activity that inhibits A549 cell proliferation.		ERK
T22830	GYY4137	GYY 4137 morpholine salt	Others
	GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity.		Others
T1801	SR9243		Liver X Receptor
	SR9243, an LXR inverse agonist, can induce LXR-corepressor interaction; shows anticancer activity and selectively targets the lipogenesis and Warburg effect.		Liver X Receptor
T60512	Haspin-IN-3		Haspin Kinase
	Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.		Haspin Kinase
T6799	IITZ-01		Apoptosis , PI3K , Autophagy
	IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)		Apoptosis , PI3K , Autophagy

Compounds

9-ING-41

T14066

Synonym:

Target: Apoptosis, GSK-3, Autophagy

(S)-crizotinib

T6357

Synonym: ent-crizotinib

Target: Apoptosis, DNA/RNA Synthesis, MTH1

Procarbazine hydrochloride

T1488

Synonym: NSC-77213 HCl,Procarbazine HCl

Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis

Ralitoline

T28503

Synonym: GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum

Target: Histone Methyltransferase

Emzadirib

T12682

Synonym: CYT-0851,RAD51-IN-2

Target: DNA/RNA Synthesis

Stilbamidine

T13905

Synonym: Ba 2652,Stilbamidin

Target: Phospholipase, Autophagy

Synonym: 17-DMAG,KOS1022,KOS 1022,KOS-1022

Target: HSP

Zeniplatin

T35300

Synonym: Zeniplatinum

Target: Others

Glufosfamide

T15390

Synonym: D 19575,Glucosylifosfamide mustard

Synonym: Cytenamide,AY-15613

Target: Microtubule Associated, HIF

Target: DNA/RNA Synthesis

Deferasirox (Fe3+ chelate)

Target: Epigenetic Reader Domain

5,7-Dimethoxy-4-methylcoumarin

Synonym: CCCI 01,CCCI01,Centrosome Clustering Chemical Inhibitor-01

Target: IRAK, MAPK, CDK

Mopidamol

T25829

Synonym: RA233,RA 233,RA-233,Rapenton,OLX 102

Target: Microtubule Associated

VU 0364739 hydrochloride

T23512

Synonym: VU 0364739 HCl

Target: Apoptosis, Phospholipase

EMD-503982

T27257

Synonym: EMD503982,EMD 503982

Synonym: MMP-13 Inhibitor

Target: MMP

Phenformin

T20158

Synonym: Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps

Target: Apoptosis, Autophagy

SRX3177

T69742

Synonym:

Target: Epigenetic Reader Domain, PI3K, CDK

Anticancer agent 46

Target: Apoptosis, Akt, PI3K, mTOR

AMD 3465 hexahydrobromide

T7208

Synonym: GENZ-644494 (hexahydrobromide)

Target: HIV Protease, CXCR

Synonym: GYY 4137 morpholine salt

Target: Liver X Receptor

Haspin-IN-3

T60512

Synonym:

Target: Haspin Kinase

IITZ-01

T6799

Synonym:

Target: Apoptosis, PI3K, Autophagy

カタログ番号	製品名	別名	ターゲット
T2763	Panaxadiol	20(R)-Panaxadiol	Others , HIF/HIF Prolyl-Hydroxylase
	Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.		Others , HIF/HIF Prolyl-Hydroxylase
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T0687	Simvastatin	MK-0733,MK 733	Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
T4952	9-Hydroxycamptothecin	9-HCPT,10-Hydroxycampothecin	Topoisomerase
	9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.		Topoisomerase
TN7226	2-Hydroxy-3-methoxy chalcone
	2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer.
TN1872	Linderone		Others
	Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line.		Others
T3S1957	9-amino-CPT	Aminocamptothecin,9-amino-2(S)-camptothecin,9-Aminocamptothecin	Topoisomerase
	9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity.		Topoisomerase
T3S1265	Liriopesides B	Nolinospiroside F	Others
	Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells.		Others
T5S1252	Prosapogenin A	Progenin III	Apoptosis , Others
	Prosapogenin A (Progenin III) has anticancer activity.		Apoptosis , Others
T8213	Isolinderalactone		NOS , STAT
	Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.		NOS , STAT
T6S0141	Corylin		Antibacterial , Antibiotic , STAT
	Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.		Antibacterial , Antibiotic , STAT
T19154	5-Methyl-2-thiophenecarboxaldehyde		Others
	5-Methyl-2-thiophenecarboxaldehyde is a candidate microscopic third-order nonlinear optical (NLO) material.5-Methyl-2-thiophenecarboxaldehyde possesses a wide range of biological activities, such as anticancer activity.		Others
T4S2012	Dihydrosanguinarine	13,14-Dihydrosanguinarine,Dihydro Sanguinarine	Caspase , Antifungal
	Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa,and has antifungal and anticancer activity.		Caspase , Antifungal
T3819	Ursolic acid acetate	Acetylursolic acid,3-Acetylursolic Acid	AChE
	Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition ...		AChE
T0595	Naringin	Naringoside	Mitophagy , P450 , Endogenous Metabolite , Autophagy
	Naringin (Naringoside), a flavanone glycoside, exerts various of pharmacological effects such as blood lipid lowering, antioxidant activity, anticancer activity, and inhibition of cytochrome P450 enzymes.		Mitophagy , P450 , Endogenous Metabolite , Autophagy
T10584	Bovinic acid	(9Z,11E)-Octadecadienoic acid,Rumenic acid	Endogenous Metabolite
	Bovinic acid ((9Z,11E)-Octadecadienoic acid) is a conjugated linoleic acid with anticancer and anti-atherosclerotic activity and can be used to study coronary heart disease and obesity in the elderly.		Endogenous Metabolite
T4S0051	Coptisine sulfate		Indoleamine 2,3-Dioxygenase (IDO)
	1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.		Indoleamine 2,3-Dioxygenase (IDO)
T8201	Gambogenic acid		Histone Methyltransferase
	Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.		Histone Methyltransferase
T2S0837	Astragalus Polysacharin	2-(Chloromethyl)-4-(4-nitrophenyl)thiazole,89250-26-0	TAM Receptor
	2-(Chloromethyl)-4-(4-nitrophenyl)thiazole is a natural product derived from Astragalus propinquus.2-(Chloromethyl)-4-(4-nitrophenyl)thiazole exhibits anticancer activity. 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole posse...		TAM Receptor
T2831	Glycocholic acid	Glycocholate,cholylglycine	Others , Endogenous Metabolite
	Glycocholic acid (Glycocholate) is a bile acid with anticancer activity. Glycocholic acid targets against pump resistance-related and non-pump resistance-related pathways.		Others , Endogenous Metabolite
TN1894	Luteolin-4'-O-glucoside	Luteolin-4'-glucoside,Luteolin-4-o-glucoside	IL Receptor
			IL Receptor
TN3543	Bruceoside A		Others
	Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.		Others
T3898	Schaftoside	APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside	Dynamin , Antioxidant , TLR , MyD88 , Mitochondrial Metabolism , Autophagy
	Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.
T36528	Illudin M		Apoptosis , DNA Alkylator/Crosslinker
	Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It has a cytotoxicity of 6-100 nM against HL-60 human leukemia cells.Illudin M has anticancer activity and is a pre-drug for the synt...		Apoptosis , DNA Alkylator/Crosslinker
T7059	α-Dihydroartemisinin	α-Artenimol,α-Dihydroqinghaosu	Parasite
	α-Dihydroartemisinin (α-Dihydroqinghaosu) is an intermediate of artemisinin-based antimalarial compounds with good antimalarial and anticancer activity, and can be used in the study of lupus erythematosus.		Parasite
T3339	Sophoridine	5-Epidihydrosophocarpine,Dihydro-5-episophocarpine	Apoptosis , Topoisomerase
	Sophoridine (Dihydro-5-episophocarpine), a natural anticancer drug, has been used in China for decades. A series of novel N-substituted Sophoridinic acid derivatives were synthesized and evaluated for their cytotoxicity ...		Apoptosis , Topoisomerase
T7441	Cuminaldehyde	Cuminic aldehyde,Cuminal	Endogenous Metabolite
	Cuminaldehyde (Cuminal) is a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity,with a pleasant smell and contributes to the aroma of essenti...		Endogenous Metabolite
TQ0309	Glaucocalyxin B		Autophagy
			Autophagy
T3425	Polyphyllin G	Polyphyllin VII,Polyphyllin VII,Y-0166	Others
	Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocel...		Others
T5S1285	(+)-(3R,8S)-Falcarindiol	Falcarindiol	Others
	1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a nov...		Others
T83321	4-Demethyldeoxypodophyllotoxin		Chk
	4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.		Chk
T3391	Corosolic acid	Corsolic acid,2α-Hydroxyursolic acid,Glucosol,Colosolic acid,Colosic acid	FAK , Autophagy
	Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by induci...		FAK , Autophagy
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy
T7054	N-Benzoyl-(2R,3S)-3-phenylisoserine	taxol side chain	Antiviral
	N-Benzoyl-(2R,3S)-3-phenylisoserine (taxol side chain) is an intermediate in the preparation of potent anticancer drug Paclitaxel, used to study the location of the binding sites. It shows cytotoxic, antiviral and immuno...		Antiviral
TN1727	Helichrysetin		Apoptosis , HIV Protease
	Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.		Apoptosis , HIV Protease
TN1019	Beta-mangostin	β-Mangostin	Apoptosis , Antibacterial , Parasite
	Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo...		Apoptosis , Antibacterial , Parasite
TN2083	Pinostrobin chalcone
	Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 c...
T3404	Cucurbitacin B	Cuc B,DATISCACIN,Amarine	Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy
	Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh...
TN1040	Skullcapflavone II		COX , Antibacterial , TGF-beta/Smad
	Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of al...		COX , Antibacterial , TGF-beta/Smad
TNU0052	Nebularine	9-(beta-D-Ribofuranosyl)-9H-purine	Apoptosis
	Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.The anticancer mechanism of Nebulari...		Apoptosis
TN3628	Chamaejasmenin B		Others
	Chamaejasmenin B is a compound isolated from Stellera chamaejasme L. Chamaejasmenin B has anticancer and antitumor activity, inhibiting cancer cell migration and invasion, and inhibiting tumor metastasis.Chamaejasmenin B...		Others
T3410	Momordin Ic	Momordin 1c	Apoptosis , MAPK , PI3K
	Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. A...		Apoptosis , MAPK , PI3K
T5S2017	Ingenol	(-)-Ingenol	PKC
	1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV...		PKC
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
TN1065	Hirsutine		Apoptosis
	Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation acti...		Apoptosis
T30969	Clitocine		Apoptosis , BCL
	Clitocine, an adenosine analogue derived from mushrooms, is a potent transcriptional readout agent, an inhibitor of nonsense mutations, and has anticancer activity, inducing the production of p53 protein in cells carryin...		Apoptosis , BCL
TN1249	3-Epiursolic acid		Cysteine Protease , Immunology/Inflammation related
	3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered p...		Cysteine Protease , Immunology/Inflammation related
T4S1050	Pristimerin	Celastrol methyl ester	NF-κB , Antibacterial
	1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...		NF-κB , Antibacterial
T4S1335	Daphnoretin	Dephnoretin,Thymelol	Influenza Virus , Caspase , PKC
	1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ...		Influenza Virus , Caspase , PKC
T25664	Lepidiline A	Macaline A	Others
	Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a...		Others
------------------------ More ------------------------

天然物製品

Panaxadiol

T2763

Synonym: 20(R)-Panaxadiol

Target: Others, HIF/HIF Prolyl-Hydroxylase

Synonym: MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

9-Hydroxycamptothecin

T4952

Synonym: 9-HCPT,10-Hydroxycampothecin

Target: Topoisomerase

2-Hydroxy-3-methoxy chalcone

Synonym: Aminocamptothecin,9-amino-2(S)-camptothecin,9-Aminocamptothecin

Target: Topoisomerase

Liriopesides B

T3S1265

Synonym: Nolinospiroside F

Target: Others

Prosapogenin A

T5S1252

Synonym: Progenin III

Target: Apoptosis, Others

Target: Antibacterial, Antibiotic, STAT

5-Methyl-2-thiophenecarboxaldehyde

Synonym: 13,14-Dihydrosanguinarine,Dihydro Sanguinarine

Target: Caspase, Antifungal

Ursolic acid acetate

T3819

Synonym: Acetylursolic acid,3-Acetylursolic Acid

Target: Mitophagy, P450, Endogenous Metabolite, Autophagy

Bovinic acid

T10584

Synonym: (9Z,11E)-Octadecadienoic acid,Rumenic acid

Target: Endogenous Metabolite

Coptisine sulfate

T4S0051

Synonym:

Target: Indoleamine 2,3-Dioxygenase (IDO)

Gambogenic acid

T8201

Synonym:

Target: Histone Methyltransferase

Astragalus Polysacharin

T2S0837

Synonym: 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole,89250-26-0

Target: TAM Receptor

Glycocholic acid

T2831

Synonym: Glycocholate,cholylglycine

Target: Others, Endogenous Metabolite

Luteolin-4'-O-glucoside

TN1894

Synonym: Luteolin-4'-glucoside,Luteolin-4-o-glucoside

Synonym: APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside

Target: Dynamin, Antioxidant, TLR, MyD88, Mitochondrial Metabolism, Autophagy

Illudin M

T36528

Synonym:

Target: Apoptosis, DNA Alkylator/Crosslinker

α-Dihydroartemisinin

T7059

Synonym: α-Artenimol,α-Dihydroqinghaosu

Target: Parasite

Sophoridine

T3339

Synonym: 5-Epidihydrosophocarpine,Dihydro-5-episophocarpine

Target: Apoptosis, Topoisomerase

Cuminaldehyde

T7441

Synonym: Cuminic aldehyde,Cuminal

Target: Endogenous Metabolite

Synonym: Polyphyllin VII,Polyphyllin VII,Y-0166

Target: Others

(+)-(3R,8S)-Falcarindiol

T5S1285

Synonym: Falcarindiol

Target: Others

4-Demethyldeoxypodophyllotoxin

Synonym: Corsolic acid,2α-Hydroxyursolic acid,Glucosol,Colosolic acid,Colosic acid

Target: FAK, Autophagy

Icaritin

T3398

Synonym: Anhydroicaritin,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

N-Benzoyl-(2R,3S)-3-phenylisoserine

T7054

Synonym: taxol side chain

Target: Apoptosis, HIV Protease

Beta-mangostin

TN1019

Synonym: β-Mangostin

Target: Apoptosis, Antibacterial, Parasite

Synonym: Cuc B,DATISCACIN,Amarine

Target: Apoptosis, PTEN, Integrin, Endogenous Metabolite, HIF, STAT, Autophagy

Skullcapflavone II

TN1040

Synonym:

Target: COX, Antibacterial, TGF-beta/Smad

Nebularine

TNU0052

Synonym: 9-(beta-D-Ribofuranosyl)-9H-purine

Target: Apoptosis, MAPK, PI3K

Target: Apoptosis, BCL, COX, UGT

Target: Apoptosis, BCL

3-Epiursolic acid

TN1249

Synonym:

Target: Cysteine Protease, Immunology/Inflammation related

Pristimerin

T4S1050

Synonym: Celastrol methyl ester

Target: NF-κB, Antibacterial

Daphnoretin

T4S1335

Synonym: Dephnoretin,Thymelol

Target: Influenza Virus, Caspase, PKC

--------- More ---------

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01865	BLMH Protein, Mouse, Recombinant (His)	Mouse	E. coli
	The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide...
TMPY-02072	HSF1 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock...

BLMH Protein, Mouse, Recombinant (His)

TMPY-01865

Species: Mouse

Expression System: E. coli

HSF1 Protein, Human, Recombinant (His)

TMPY-02072

Species: Human

Expression System: E. coli

カタログ番号	製品名
L6110	Alkaloid Natural Product Library	464 compounds
	A unique collection of 464 natural alkaloids can be used for high throughput and high content screening；
L2160	Anti-Cancer Active Compound Library	3188 compounds
	A unique collection of 3188 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L1100	Protease Inhibitor Library	343 compounds
	A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
L6700	Anti-Tumor Natural Product Library	1772 compounds
	A unique collection of 1772 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Alkaloid Natural Product Library

L6110

Compounds: 464

Anti-Cancer Active Compound Library

L2160

Compounds: 3188

Protease Inhibitor Library

L1100

Compounds: 343

Anti-Tumor Natural Product Library

L6700

Compounds: 1772